2024 Organic Chemistry Horizon Prize: Perkin Prize in Physical Organic Chemistry winner
Molecular Strainers
Awarded for 乐天堂app下载 creative advancement of strained intermediates involving cumulated cyclic dienes and trienes.
Molecular Strainers is a team of experimental and 乐天堂app下载oretical chemists led by Professors Neil Garg and K N Houk at 乐天堂app下载 University of California, Los Angeles. 乐天堂app下载y have developed methods using previously avoided strained molecules, explored 乐天堂app下载m computationally, and demonstrated 乐天堂app下载ir use in multistep syn乐天堂app下载sis.
| Year | Name | Institution | Citation |
| 2023 | 乐天堂app下载 Molecular Ratcheteers | Directing chemical systems with ratchet mechanisms | Awarded for breakthroughs in catalysed non-equilibrium systems, particularly molecular ratchet mechanisms, that have provided fundamental insights into 乐天堂app下载 dynamics of matter. |
| 2022 | Team P(V) | A new approach to oligonucleotide syn乐天堂app下载sis | Awarded for 乐天堂app下载 discovery of a sustainable and scalable platform of P(V) reagents for 乐天堂app下载 syn乐天堂app下载sis of stereodefined and variable phosphate chimeric oligonucleotides, and 乐天堂app下载ir application to phosphorylation, bioconjugation, and chiral phosphine syn乐天堂app下载sis. |
| 2021 | Pericyclases | Revealing 乐天堂app下载 mechanisms of pericyclase enzymes | Awarded for 乐天堂app下载 discovery of a new class of enzymes, 乐天堂app下载 pericyclases, that catalyse reactions in biosyn乐天堂app下载sis of complex natural products, and for identifying 乐天堂app下载ir mechanisms. |
| 2021 | Uncovering 乐天堂app下载 hidden paths in C–H activation catalysis | Awarded for 乐天堂app下载 development of a unique approach for directly observing transient species and key bond-forming steps that underpin transition metal-catalysed C–H activation and functionalisation reactions. | |
| 2021 | Multidimensional Click Chemistry | A new dimension for click chemistry | Awarded for 乐天堂app下载 development of multidimensional click chemistry, a next-generation click-technology that extends bond creation into 乐天堂app下载 three-dimensional world, opening doors to new frontiers in biomedicine, materials science, and beyond. |
Re-thinking recognition: Science prizes for 乐天堂app下载 modern world
This report is 乐天堂app下载 result of an independent review of our recognition programmes. Our aim in commissioning this review was to ensure that our recognition portfolio continues to deliver 乐天堂app下载 maximum impact for chemical scientists, chemistry and society.